A policy analysis of the national phenylketonuria screening program in Iran

Abstract Background Phenylketonuria (PKU) screening is a public health measure taken to diagnose and treat the patients with PKU prevent severe neurological disorders in them. The present study was aimed at analyzing policies of national (NaPS) program Iran. Methods were analyzed compliance policy triangle model. Document review 38 semi-structured interviews used for data collection. using content analysis, interview framework analysis. Results decision made genetics department Ministry Health Medical Education (MOHME) Many internal external stakeholders involved it valid evidence formulate policies. Despite some opposition insufficient support, implemented due continuous persistence parents, interested executives, formulated top-down approach. main barriers included rapid substitution managers, shortage Phe-free milk, little awareness patients’ families, social stigma, inadequate co-operation hospital administrators. Conclusions contributed explaining different components program. A successful requires more stability senior managers MOHME, enough human resources educating commitment hospitals Meanwhile, all need be effectively.